業 績 集


Original papers (2000~2008)

2008

Nakanishi H, Iida Y, Shimizu T, Taguchi R. Analysis of oxidized phosphatidylcholines as markers for oxidative stress, using multiple reaction monitoring with theoretically expanded data sets with reversed-phase liquid chromatography/tandem mass spectrometry. J Chromatogr B ; in press

Ogiso H, Taguchi R. Reversed-Phase LC/MS Method for Polyphosphoinositide Analyses: Changes in Molecular Species Levels during Epidermal Growth Factor Activation in A431 Cells. Anal Chem. ; 80(23):9226-9232. 2008

Hayasaka T, Goto-Inoue N, Sugiura Y, Zaima N, Nakanishi H, Ohishi K, Nakanishi S, Naito T, Taguchi R, Setou M. Matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight (MALDI-QIT-TOF)-based imaging mass spectrometry reveals a layered distribution of phospholipid molecular species in the mouse retina. Rapid Commun Mass Spectrom.; 22(21):3415-26. 2008

Sato H, Kato R, Isogai Y, Saka GI, Ohtsuki M, Taketomi Y, Yamamoto K, Tsutsumi K, Yamada J, Masuda S, Ishikawa Y, Ishii T, Kobayashi T, Ikeda K, Taguchi R, Hatakeyama S, Hara S, Kudo I, Itabe H, Murakami M. Analyses of Group III Secreted Phospholipase A2 Transgenic Mice Reveal Potential Participation of This Enzyme in Plasma Lipoprotein Modification, Macrophage Foam Cell Formation, and Atherosclerosis. J Biol Chem. ; 283(48):33483-33497, 2008

Ikeda K, Shimizu T, Taguchi R. Targeted analysis of ganglioside and sulfatide molecular species by LC/ESI-MS/MS with theoretically expanded multiple reaction monitoring. J Lipid Res.;49(12):2678-89, 2008

Oka T, Itoi T, Terada N, Nakanishi H, Taguchi R, Hamaoka K. Change in the membranous lipid composition accelerates lipid peroxidation in young rat hearts subjected to 2 weeks of hypoxia followed by hyperoxia. Circ J.; 72(8):1359-66, 2008

Tanaka K, Fukuda R, Ono Y, Eguchi H, Nagasawa S, Nakatani Y, Watanabe H, Nakanishi H, Taguchi R, Ohta A.: Incorporation and remodeling of extracellular phosphatidylcholine with short acyl residues in Saccharomyces cerevisiae. Biochim Biophys Acta.; 1781(8):391-9, 2008

Okuno T, Iizuka Y, Okazaki H, Yokomizo T, Taguchi R, Shimizu T: 12(S)-Hydroxyheptadeca-5Z, 8E, 10E-trienoic acid is a natural ligand for leukotriene B4 receptor 2. J. Exp. Med.;205(4):759-66. 2008

Tsumoto H, Ra M, Samejima K, Taguchi R, Kohda K.Cemicalm derivatization of peptides containing phosphorylated serine/threonine for efficient ionization and quantification in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom.; 22(7):965-72. 2008

Ogiso H, Suzuki T, Taguchi R., Development of a reverse-phase liquid chromatography electrospray ionization mass spectrometry method for lipidomics, improving detection. Anal Biochem.; 375(1):124-31. 2008

Hishikawa D, Shindou H, Kobayashi S, Nakanishi H, Taguchi R, Shimizu T., Discovery of a lysophospholipid acyltransferase family essential for membrane asymmetry and diversity. Proc Natl Acad Sci USA.; 105(8):2830-5. 2008

2007

Tsumoto H, Murata C, Miyata N, Kohda K, Taguchi R. Efficient identification and quantification of proteins using isotope-coded 1-(6-methylnicotinoyloxy) succinimides by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom.; 21(23):3815-24, 2007

Shindou H, Hishikawa D, Nakanishi H, Harayama T, Ishii S, Taguchi R, Shimizu T. A single enzyme catalyzes both PAF production and membrane biogenesis of inflammatory cells: cloning and characterization of acetyl-CoA:lyso-PAF acetyltransferase. J Biol Chem. 282, 6532-6539, 2007

Houjou T, Hayakawa J, Watanabe R, Tashima Y, Maeda Y, Kinoshita T, Taguchi R.. Changes in molecular species profiles of glycosylphosphatidylinositol anchor precursors in early stages of biosynthesis. J Lipid Res. 48:1599-606, 2007

Maeda Y, Tashima Y, Houjou T, Fujita M, Yoko-o T, Jigami Y, Taguchi R, Kinoshita T. Fatty acid remodeling of GPI-anchored proteins is required for their raft association. Mol Biol Cell. 18:1497-506. 2007

Nakashima H, Hamamura K, Houjou T, Taguchi R, Yamamoto N, Mitsudo K, Tohnai I, Ueda M, Urano T, Furukawa K, Furukawa K.. Overexpression of caveolin-1 in a human melanoma cell line results in dispersion of ganglioside GD3 from lipid rafts and alteration of leading edges, leading to attenuation of malignant properties. Cancer Sci.; 98:512-20, 2007

Nakano-Kobayashi A, Yamazaki M, Unoki T, Hongu T, Murata C, Taguchi R, Katada T, Frohman MA, Yokozeki T, Kanaho Y. Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis. EMBO J.; 26:1105-16, 2007

Shindou H, Hishikawa D, Nakanishi H, Harayama T, Ishii S, Taguchi R, Shimizu T. A single enzyme catalyzes both PAF production and membrane biogenesis of inflammatory cells: cloning and characterization of acetyl-CoA:lyso-PAF acetyltransferase. J Biol Chem. 282, 6532-6539, 2007

2006

Oike H, Wakamori M, Mori Y, Nakanishi H, Taguchi R, Misaka T, Matsumoto I, and Abe K. Arachidonic acid can function as a signaling modulator by activating the TRPM5 cation channel in taste receptor cells. Biochim Biophys Acta. 1761, 1078-1084, 2006

Nakanishi H, Shindou H, Hishikawa D, Harayama T, Ogasawara R, Suwabe A, Taguchi R, Shimizu T. Cloning and characterization of mouse lung-type acyl-CoA:lysophosphatidylcholine acyltransferase 1 (LPCAT1). Expression in alveolar type II cells and possible involvement in surfactant production. J. Biol. Chem. 281, 20140-20147, 2006

Tashima Y, Taguchi R, Murata C, Ashida H, Kinoshita T, Maeda Y. PGAP2 is essential for correct processing and stable expression of GPI-anchored proteins. Mol Biol Cell. 17,1410-1420, 2006

2005

Taguchi R, Houjou T, Nakanishi H, Yamazaki T, Ishida M, Imagawa M, Shimizu T. Focused lipidomics by tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 823:26-36, 2005

Ishida M, Imagawa M, Shimizu T, Taguchi R. Effective extraction and analysis for lysophosphatidic acids and their precursors in human plasma using electrspray ionization mass spectrometry. J. Mass Spectrom. Soc. Jpn. 53, 217-226, 2005

Houjou, T., Yamatani, K., Imagawa, M., Shimizu, T., Taguchi, R. A Shotgun tandem mass spectrometric analysis of phospholipids with normal-phase and/or reverse-phase liquid chromatography/electrospray ionization mss spectrometry. Rapid Commun. Mass Spectrom., 19, 654-666, 2005

Ishida M, Imagawa M, Shimizu T, Taguchi R. Specific detection of lysophosphatidic acids in serum extracts by tandem mass spectrometry. J. Mass Spectro. Soc. Jpn. 53, 25-32, 2005

Kondoh G, Tojo H, Nakatani Y, Komazawa N, Murata C, Yamagata K, Maeda Y, Kinoshita T, Okabe M, Taguchi R, Takeda J. Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization. Nat Med.; 11:160-166, 2005

2004

Houjou, T., Yamatani, K., Nakanishi, H., Imagawa, M., Shimizu, T., Taguchi. R. Rapid and selective identification of molecular species in phosphatidylcholine and sphingomyelin by conditional neutral loss scanning and MS. Rapid Commun. Mass Spectrom., 18: 3123-3130, 2004

Ishida, M., T. Yamazaki, T. Houjou, M. Imagawa, A. Harada, K. Inoue, and R. Taguchi. High-resolution analysis by nano-electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry for the identification of molecular species of phospholipids and their oxidized metabolites. Rapid Commun Mass Spectrom. 18:2486, 2004

Tsuchiya, S., Emi Arimoto, E., Nishizuka, M., Taguchi, R., and Imagawa, M. Isolation of Genes Regulated by Peroxisome Proliferator-Activated Receptor γ(PPARγ) by Two-Dimensional Electrophoresis and Mass Spectrometry. Journal of Health Science, 50:257-263, 2004

Kawamoto, Y., Takeda, K., Okuno, Y., Yamakawa, Y., Ito, R., Taguchi, R., Kato, M., Suzuki, H., Takahashi, M., and Nakashima. I. Identification of RET autophosphorylation sites by mass spectrometry. J Biol Chem. 279:14213-24, 2004

2003

Tsumoto, H., C. Murata, N. Miyata, R. Taguchi, and K. Kohda. 2003. Preparation of deuterated methyl and dimethyl substituted nicotinoylating agents for derivatization of the N-terminal of protein. Chem Pharm Bull (Tokyo). 51:1399-401, 2003

Hiramatsu, T., H. Sonoda, Y. Takanezawa, R. Morikawa, M. Ishida, K. Kasahara, Y. Sanai, R. Taguchi, J. Aoki, and H. Arai Biochemical and molecular characterization of two phosphatidic acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1beta. J Biol Chem. 278:49438-47, 2003

Asai, K., T. Hirabayashi, T. Houjou, N. Uozumi, R. Taguchi, and T. Shimizu Human group IVC phospholipase A2 (cPLA2gamma). Roles in the membrane remodeling and activation induced by oxidative stress. J Biol Chem. 278:8809-14, 2003

2002

Tauchi-Sato, K., S. Ozeki, T. Houjou, R. Taguchi, and T. Fujimoto The surface of lipid droplets is a phospholipid monolayer with a unique Fatty Acid composition. J Biol Chem. 277:44507-12, 2002

Sonoda, H., J. Aoki, T. Hiramatsu, M. Ishida, K. Bandoh, Y. Nagai, R. Taguchi, K. Inoue, and H. Arai A novel phosphatidic acid-selective phospholipase A1 that produces lysophosphatidic acid. J Biol Chem. 277:34254-63, 2002

Aoki, J., A. Taira, Y. Takanezawa, Y. Kishi, K. Hama, T. Kishimoto, K. Mizuno, K. Saku, R. Taguchi, and H. Arai. Serum lysophosphatidic acid is produced through diverse phospholipase pathways. J Biol Chem. 277:48737-44, 2002

2001

H. Hosono, J. Aoki, Y. Nagai, K. Bandoh, M. Ishida, R. Taguchi, H. Arai, K. Inoue: Phosphatidylserine-specific phospholipase A1 stimulates histamine release from rat peritoneal mast cells through production of 2-acyl-1-lysophosphatidylserine. J. Biol. Chem., 276, 29664-29670, 2001

K. Yokoyama, S. Saitoh, M. Ishida, Y. Yamakawa, K. Nakamura, K. Inoue, R. Taguchi, A. Tokumura, M. Nishijima, M. Yanagida, M. Setaka: Very-long-chain fatty acid-containing phospholipids accumulate in fatty acid synthase temperature-sensitive mutant strains of the fission yeast Schizosaccharomyces pombe fas2/lsd1. Biochim. Biophys. Acta. 1532, 223-233, 2001

2000

R. Taguchi, J. Hayakawa, Y. Takeuchi, M. Ishida: Two-dimensional analysis of phospholipids by capillary liquid chromatography/electrospray ionization mass spectrometry. J. Mass Spectrom., 35, 953-966, 2000

1999年以前